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2002429
HLA-B*57:01 for Abacavir Sensitivity
HLA-B5701
Ordering Recommendation
Standard of care prior to abacavir therapy per FDA. Predicts risk of abacavir hypersensitivity syndrome. Relevant to most populations.
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma or serum. Heparinized specimens. Frozen specimens in glass collection tubes.
Remarks
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month.
Methodology
Polymerase Chain Reaction/Fluorescence Monitoring
Performed
Varies
Reported
5-10 days
Reference Interval
By report
Interpretive Data
Refer to Report
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Compliance Category
Laboratory Developed Test (LDT)
Note
Hotline History
N/A
CPT Codes
81381
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2002431 | HLA-B*57:01 Specimen | 31208-2 |
| 2002432 | HLA-B*57:01 Allele | 50956-2 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Abacavir hypersensitivity genotyping
- Abacavir Sensitivity
- HLA-B 5701 Genotype, Abacavir Hypersensitivity, Saliva
HLA-B*57:01 for Abacavir Sensitivity
